Rare meets routine: A case of sessile serrated lesion presenting as acute appendicitis

• Author Details:   
• Syed Mubid Ali
• Mohammed Abdullah Masood ^*
• Naushaba Tazeen
• Asiya Tabassum
• Idrees Akhtar Afroze
• Atiya Begum
• Shireen Adeeb Mujtaba Ali

---

View PDF

Sessile serrated lesions (SSLs) are rare premalignant neoplasms usually arising in the colon but can also occur in the appendix, where their presentation often mimics acute appendicitis. We report the case of a 68‑year‑old male who presented with right lower abdominal pain and imaging findings suggestive of acute appendicitis with appendicular mucocele. The patient underwent appendectomy, and histopathological examination of the resected specimen revealed a sessile serrated lesion with marked dysplasia, without evidence of adenocarcinoma. Appendiceal SSLs are seldom reported in literature and may be overlooked due to their nonspecific clinical and radiological features. As SSLs are important precursors of colorectal carcinoma via the serrated neoplasia pathway, meticulous histopathological evaluation is crucial for accurate diagnosis. Early recognition, surgical excision, and colonoscopic follow‑up can help prevent malignant transformation. This case adds to the limited literature on appendiceal SSLs and emphasizes the need for increased awareness and documentation.