A study of endometrial biopsies with clinico-radiological and histopathological correlates at a tertiary care center

• Author Details:   
• Bimal Patel ^*
• Jaydip Gorani

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Background: Endometrial biopsies are important gynaecological diagnostic tool which helps understand endometrial pathology, particularly in the context of menorrhagia and abnormal uterine bleeding (AUB).

Aim and Objectives: To study and correlate endometrial biopsies with clinical presentations, age distribution, endometrial thickness, hormone use and histopathological findings.

Results: A cohort of 305 patients underwent endometrial biopsies for various gynaecological symptoms, of which menorrhagia was the most common, followed by perimenopausal and postmenopausal bleeding. Endometrial thickness on ultrasound was 4mm (median) in functional endometrial changes, while >6mm in endometrial hyperplasia, polyps and carcinoma. On histopathology, functional endometrial change (proliferative/secretory) was the most common findings among the different age groups, disordered proliferation of endometrium (DPE) in 9.8% cases, endometrial hyperplasia in 12.02% cases and carcinoma in 1.96% cases. Pregnancy related changes were noted in 2.28% cases.

Conclusion: Endometrial biopsies are simple, cost effective procedure and provide valuable information in understanding endometrial pathology for better management of patients.