- Visibility 16 Views
- Downloads 9 Downloads
- Permissions
- DOI 10.18231/j.ijpo.12809.1760416186
-
CrossMark
- Citation
Plasma cell rich effusions and its concurrence with plasma cell neoplasms- A case series
- Author Details:
-
Kirthi Nath K V
-
Soumya Satheesh
-
Aardra Rageesh *
Plasma cell neoplasms are clonal hematologic malignancies that represent 10% of all hematologic neoplasms. Incidence increases with advancing age and early diagnosis is rewarding due to great treatment amenability. Diagnosis of this malignancy requires a combination of clinical, biochemical, immunoelectrophoretic and bone marrow findings each with its due. Plasma cell rich effusions that do not form a part of diagnostic algorithm was identified as an incidental finding in 1 case of suspected plasma cell neoplasm and another confirmed case of plasma cell leukemia at our center is being described in this article. The value of plasma cell rich effusion as an associated finding in aggressive cases of plasma cell myeloma is being described here in correlation with the available literature. Immunocytochemical workup for kappa and lambda light chains could not identify e restriction and proved inconclusive in both the cases. The article aims to add to the existing literature on the same topic.
References
- Fend F, Dogan A, Cook JR. Plasma cell neoplasms and related entities—evolution in diagnosis and classification. Virchows Arch. 2022;482(1):163–77. https://doi.org/10.1007/s00428-022-03431-3
[Google Scholar] - Kyle RA, Steensma DP. History of multiple myeloma. Recent Results Cancer Res. 2011;183:3–23. https://doi.org/10.1007/978-3-
[Google Scholar] 540-85772-3_1. - Sewpersad S, Pillay TS. Historical perspectives in clinical pathology: Bence Jones protein—early urine chemistry and the impact on modern day diagnostics. J Clin Pathol. 2021;74(4):212–
- https://doi.org/10.1136/jclinpath-2020-206675
[Google Scholar] - Silva C, Costa A, Paiva D, Freitas S, Alves G, Cotter J. Light-Chain Multiple Myeloma: A Diagnostic Challenge. Cureus. 2021;13(10):e19131. https://doi.org/10.7759/cureus.19131
[Google Scholar] - Gochhait D, Dey P, Verma N. Cytology of plasma cell rich effusion in cases of plasma cell neoplasm. J Cytol. 2016;33(3):150–3. https://doi.org/10.4103/0970-9371.177147
[Google Scholar] - Baksh M, Li K, Jiang L, Alegria V, Sher T, Roy V, et al. Myelomatous ascites and pleural effusion in relapsed multiple myeloma. Clin Case Rep . 2022;10(2):e05329. https://doi.org/10.1002/ccr3.5329
[Google Scholar] - Greer JP, Foerster J, Lukens JN, eds. Wintrobe's Clinical Hematology. 11th ed. Lippincott Williams & Wilkins; 2003.
- De S, Samanta S, Shah M. Plasma Cells Out for a Swim! A Study on Myelomatous Involvement of Effusion Fluid and Cerebrospinal Fluid: A 10-Year Experience from a Tertiary Cancer Center. J Cytol. 2025;42(1):48–53. https://doi.org/10.4103/joc.joc_87_24
[Google Scholar]
How to Cite This Article
Vancouver
V KNK, Satheesh S, Rageesh A. Plasma cell rich effusions and its concurrence with plasma cell neoplasms- A case series [Internet]. Indian J Pathol Oncol. 2025 [cited 2025 Oct 18];12(3):267-270. Available from: https://doi.org/10.18231/j.ijpo.12809.1760416186
APA
V, K. N. K., Satheesh, S., Rageesh, A. (2025). Plasma cell rich effusions and its concurrence with plasma cell neoplasms- A case series. Indian J Pathol Oncol, 12(3), 267-270. https://doi.org/10.18231/j.ijpo.12809.1760416186
MLA
V, Kirthi Nath K, Satheesh, Soumya, Rageesh, Aardra. "Plasma cell rich effusions and its concurrence with plasma cell neoplasms- A case series." Indian J Pathol Oncol, vol. 12, no. 3, 2025, pp. 267-270. https://doi.org/10.18231/j.ijpo.12809.1760416186
Chicago
V, K. N. K., Satheesh, S., Rageesh, A.. "Plasma cell rich effusions and its concurrence with plasma cell neoplasms- A case series." Indian J Pathol Oncol 12, no. 3 (2025): 267-270. https://doi.org/10.18231/j.ijpo.12809.1760416186