Cholesterotic Fibrous Histiocytoma (CFH): A case report

Authors: Bandana Mehrotra, Supriya Mehrotra, Sanjay Mehrotra, Ashok Kumar Kapoor, Hari Shyam

DOI: 10.18231/j.ijpo.11334.1720918526

Keywords: Cholesterol-induced inflammation, Giant cells and macrophages, fibroblastic proliferation, acanthosis, hyperkeratosis

Abstract: An elderly female patient complained of a small nodule, measuring 0.3 cm³ in right upper eye-lid. Microscopically, it showed chronic inflammation. Aggregates of cholesterol crystals were seen. Several multinucleate giant cells were also seen. The patient had persistently raised hyperlipoproteinemia which might hasten the progression of cholesterotic fibrous histiocytoma. Overlying squamous epithelium showed acanthosis, hyperkeratosis and papillary processes. She was finally diagnosed as a case of cholesterotic fibrous histiocytoma (CFH).