Study of histopathological spectrum of diagnosis in lymph node biopsies in a tertiary care centre

---

Original Article

Author Details : Shwetha Pallavi M.S*, Manjunatha Y.A

Volume : 6, Issue : 3, Year : 2019

Article Page : 476-479

https://doi.org/10.18231/j.ijpo.2019.091

Suggest article by email

Get Permission

---

Abstract

Objectives: Histopathological examination of lymph node is one of the gold standard test for the diagnosis of neoplastic and non-neoplastic lesions, as lymphadenopathy is a common presentation of large variety of disorders including benign and malignant. This study aims at identifying various histopathological lesions of lymph node, their patterns and frequency of occurrence.
Materials and Methods: This retrospective study includes 70 histopathologically diagnosed cases of lymph node biopsies received by the department of pathology, Dr. B.R. Ambedkar Medical College, Bengaluru from Jan 2017 to Aug 2018. Lymph nodes sent along with known primary malignant resection specimens were excluded from the study.
Results: Out of 70 cases, non-neoplastic lesions were more common comprising of 57 cases (81.5%) and neoplastic lesions were 13 cases (18.5%).Non-neoplastic lesions included tuberculous lymphadenitis 27cases (38.5%),  non-specific reactive hyperplasia  25 cases (35.7%), specific reactive lymphadenitis 3 cases (4.2%) and other granulomatous lesions 2 cases(2.8%). Neoplastic lesions included metastasis 7 cases (10%), Hodgkin’s lymphoma 5 cases (7.1%) and non-Hodgkin’s lymphoma 1 case (1.4%).
Conclusion: Non-neoplastic diseases were more common than neoplastic diseases. Among non-neoplastic, tuberculous lymphadenitis was the most common lesion and among neoplastic lesions, metastasis was more common.

Keywords: Tuberculous lymphadenitis, Metastasis, Reactive lymphoid hyperplasia, Hodgkin lymphoma, Lymphadenopathy.

How to cite : M.s S P, Y.a M, Study of histopathological spectrum of diagnosis in lymph node biopsies in a tertiary care centre. Indian J Pathol Oncol 2019;6(3):476-479

This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.