Role of Prothrombin time International normalized ratio and activated partial thromboplastin time in beta thalassemia major: A cross sectional study

---

Original Article

Author Details : Karthik Srevatsa*, Ranjit P Kangle, Sujata M Jali

Volume : 6, Issue : 2, Year : 2019

Article Page : 237-241

https://doi.org/10.18231/j.ijpo.2019.047

Suggest article by email

Get Permission

---

Abstract

Objectives: To evaluate the changes in PT/ INR and APTT in Beta thalassemia major cases.
Materials and Methods: A cross sectional study was conducted on 100 patients diagnosed with beta thalassemia major.
Results: Mean PT was noted to be 15.58s and mean APTT was 41.05s. These were elevated than controls and statistically significant. Association between serum ferritin and INR was not statistically significant. Correlation graph analysis between age and APTT was positive and significant while that for ferritin and APTT was negative.
Conclusion: Significant alterations in PT / INR and APTT exist in beta thalassemia major patients. Additional parameters and a tailored approach is suggested.

Keywords: PT, APTT, INR beta thalassemia Major.

How to cite : Srevatsa K, Kangle R P, Jali S M, Role of Prothrombin time International normalized ratio and activated partial thromboplastin time in beta thalassemia major: A cross sectional study. Indian J Pathol Oncol 2019;6(2):237-241

This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.