Histopathological overview of central nervous system tumours in North Maharashtra, India: a single center study

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Original Article

Author Details : Shivraj Nagnath Kanthikar, Dhiraj B. Nikumbh, Nadkumar V. Dravid

Volume : 4, Issue : 1, Year : 2017

Article Page : 80-84

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Abstract

Background: Central nervous system (CNS) tumor are considered as most notorious in all types of cancers. Incidence of CNS tumors in developing countries is lower as compared to developed countries, but increased rate has been observed in both. The aim of the study was to highlight the incidence and histological spectrum of CNS tumors in our region. To diagnose and classify brain tumours according to WHO 2007 classification.
Material and Methods: This retrospective histopathological analysis of brain tumors was carried out in department of Pathology from January 2014 to December 2015. During this period, a total of 38 neurosurgical specimens were received in department. The specimens were processed by routine histotechniques and immunohistochemistry was performed whenever required. The diagnosed brain tumor studied and classified according to WHO classifications.
Results: Among 38 cases, tumours of meningeal tissue (40%) were commonest followed by neuroepithelial tissue (34%). Cranial and spinal nerve sheath tumour (18%) and rarely metastatic tumours (5.3%) were encountered. Tumours were seen in all age groups but mean age group affected was 41-50 years accounting for 14 (36.8%) cases. Male to female ratio of 0.81:1.22 was noted with female preponderance.
Conclusion: The present study helps to provide information regarding the burden of disease in our area. Despite the use of modern imaging technique that helps in provisional diagnosis of disease, histological examination is gold standard in diagnosis of varied types. Further utility of immunohistochemistry aids in confirmation and prognosis of disease.
Keywords: CNS tumours, Glioma, Meningioma, Histopathology, Immunohistochemistry

How to cite : Kanthikar S N, Nikumbh D B, Dravid N V, Histopathological overview of central nervous system tumours in North Maharashtra, India: a single center study. Indian J Pathol Oncol 2017;4(1):80-84

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