A cytohistopathological study to evaluate the diagnostic role of Fine-needle aspiration cytology (FNAC) in salivary gland lesions

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Original Article

Author Details : Rashmi Jain, Ankit Jain

Volume : 4, Issue : 1, Year : 2017

Article Page : 45-51

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Abstract

Background & Objectives: FNAC is used as a preoperative diagnostic tool to differentiate between benign and malignant salivary glands (SGs) tumors. The aim of this study was to evaluate the sensitivity, specificity and diagnostic accuracy of the FNAC for SGs lesions.
Methods: FNAC was carried out in 144 patients with various SGs lesions and classified. Out of 144 cases, only 59 cases were available for histopathological examination. FNAC diagnosis was compared with the final histological diagnosis; and then sensitivity, specificity and diagnostic accuracy of the FNAC for SGs lesions were calculated.
Results: Parotid gland was involved in 54.86% cases, whereas submandibular and minor SGs were involved in 40.27% and 4.86% cases respectively. Non-neoplastic lesions were found in 50.7% cases, whereas benign and malignant lesions were found in 36.8% and 12.5% cases respectively. Submandibular gland was commonly (52.05%) involved in non –neoplastic lesions whereas in benign and malignant lesions, parotid gland was involved 64.15% and 77.78% cases respectively. Chronic sialadenitis (58.9%), pleomorphic adenoma (90.56%) and mucoepidermoid carcinoma (55.55%) were most common lesions among non–neoplastic, benign and malignant lesions respectively. Sensitivity, specificity and diagnostic accuracy of FNAC for neoplastic SGs lesions were 87.50%, 97.44% and 94.54% respectively.
Interpretations & Conclusions: The high sensitivity, specificity and diagnostic accuracy of the FNAC indicates that it may serve as a good pre-operative diagnostic technique for SGs lesions. This study highlights the diagnostic value of FNAC in differentiating benign from malignant lesions which are useful in the planning of further management.

Keywords: Diagnostic accuracy, FNAC, Salivary gland lesions, Sensitivity

 

How to cite : Jain R, Jain A, A cytohistopathological study to evaluate the diagnostic role of Fine-needle aspiration cytology (FNAC) in salivary gland lesions. Indian J Pathol Oncol 2017;4(1):45-51

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