Indian Journal of Pathology and Oncology
Official Publication of Innovative Education and Scientific Research Foundation
Official Publication of Innovative Education and Scientific Research Foundation
Original Article
Author Details :
Volume : 4, Issue : 1, Year : 2017
Article Page : 8-11
Abstract
Background: Blood group system consists of antigens present on the surface of red blood cells. Up till now around 700 red cell antigens have been identified. The ABO grouping and Rhesus (Rh) typing are major systems and are inherited by means of Mendelian fashion. They are crucial for blood transfusions, parental testing and in certain forensic related medico legal cases. Also association of blood grouping systems can be attributed to gene associated studies in certain diseases among different population.
The distribution pattern of ABO blood grouping systems varies among people around the world and also in different regions of same country.
Aims: The study is aimed to determine the distribution pattern of the ABO grouping and Rh typing among blood donors in Dr. BR Ambedkar Medical College, Bangalore and to correlate it with the available data from studies inside India and other parts of the world.
Materials and Methods: The study included blood donors in blood bank of Dr. BR Ambedkar Medical College Hospital from July 2012 to May 2016.The study was done on 1959 blood donors. ABO grouping and Rh typing was done using slide agglutination method with antisera A, B, O and Rh. Doubtful cases were reconfirmed by tube agglutination method and reverse grouping using freshly prepared pooled A and B cells. The sex incidence of ABO and Rh blood groups were stated in simple percentages.
Results: Male donors were more than female donors, ratio being 77.3: 1.
The most common blood group was O (38.8%) and least common being AB (5%).
The distribution pattern of blood group O in our population was38.8 % (37.5% O Rh positive and 1.3% O Rh negative). The distribution pattern of blood group B in our population was 34.8% (33.9% B Rh positive and 0.9% B Rh negative) followed by blood group A which was 21.4% (21% A Rh positive and 0.4% A Rh negative) and blood group AB was 5%(4.7% AB Rh positive and 0.3% AB Rh negative) Rh positive were 97.1% and Rh negative were 2.9%.
Conclusion: Knowledge of distribution pattern of the different blood groups is very crucial for blood banks and blood transfusion services which significantly contribute to the Health System of the Nation. Knowledge of blood group distribution is important for clinical studies, geographical information and for forensic studies in the general population.
Keywords: Blood group, ABO, Rh
How to cite : Anushree Cn, Sujatha R, Patil S B, Jaya Prakash Ht, Distribution pattern of ABO grouping and Rhesus typing among blood donors: a study from a tertiary care teaching hospital blood bank of Dr. BR Ambedkar Medical College, Bangalore. Indian J Pathol Oncol 2017;4(1):8-11
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