Demographic, histopathological and staging analysis of colorectal carcinomas in a Tertiary Care Hospital, Mumbai

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Original Article

Author Details : Milind Vasant Patil, Sangita Ramulu Margam, Anjali Ajay Mahajan, Sandeep Parate, Alka D Kalgutkar

Volume : 3, Issue : 4, Year : 2016

Article Page : 636-643

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Abstract

Background: Carcinoma of the colon and rectum is a relatively uncommon malignancy in India when compared with the western world. Colorectal cancer is generally a disease affecting individuals 50 years of age and older and is much less common in persons under 40 years of age.
Aims: To study relative frequency of colonic carcinoma with regard to demographic data, histological types and pathologic stages.
Materials and methods: We studied total of 409 colorectal carcinomas (CRC), diagnosed during the past 15 years i.e., from January 2001 to December 2015. The records were analysed in detail for age, gender, site of primary tumour, histopathological type, and pathological stage.
Results: Four hundred and nine patients were diagnosed to have CRC. Majority were males (54.77%), rectum was commonest site (57.7%). Most of them were adenocarcinoma (54.52%) followed by mucin?secreting adenocarcinomas (22.49%) and squamous cell carcinoma in 9.29%. Most of them presented at IIB stage (40.09%). Patients less than 40 years (30.81%) showed less favourable histology and higher grade of tumor.
Conclusions: In CRC, rectal cancers are the most common cancers. Incidence of CRC in young is increasing. Screening for colorectal cancers and early evaluation of symptomatic cases need to be defined in developing countries.

Keywords: Adenocarcinoma, Colorectal carcinoma, Demography, Young age.

How to cite : Patil M V, Margam S R, Mahajan A A, Parate S, Kalgutkar A D, Demographic, histopathological and staging analysis of colorectal carcinomas in a Tertiary Care Hospital, Mumbai. Indian J Pathol Oncol 2016;3(4):636-643

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