The histopathological spectrum of meningeal neoplasms

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Original Article

Author Details : Nitin Maheshvar Gadgil, Sangita Ramulu Margam, Chetan Sudhakar Chaudhari, Prashant Vijay Kumavat

Volume : 3, Issue : 3, Year : 2016

Article Page : 432-436

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Abstract

Background: Meningiomas are slow-growing and benign tumor of the meninges, which line the skull and enclose the brain.
Methods: We have studied 324 cases of meningeal lesions (clinically diagnosed and histologically proved) in Department of Pathology of a tertiary care hospital. We evaluated its frequency, age and sex distribution and documented as per the WHO histological grade of meningioma.
Results: The commonest age group affected was 41-60 years. Female predominance was seen. Headache being most common symptom with commonest site was intracranial (88.2%). The meningeal lesions consisted of meningioma (96.6%) and non-meningioma lesions (3.4%). The commonest histopathological type of mengioma was transitional (24.2%) followed by meningotheliomatous (22.8%). The 85.6% of the meningioma was WHO Grade I tumor. For WHO Grade II meningiomas, mitotic figures and high cellularity was helpful to diagnose the tumors. The non-meningioma lesions included hemangiopericytoma, solitary fibrous tumor, malignant melanoma and metastasis by carcinoma breast, lung and thyroid.
Conclusion: From our study, we can conclude that benign meningiomas WHO grade I are most common. Intracranial location is the most common for meningioma. Middle-aged group of 41–60 years was predominently affected and it is uncommon in children.

Keywords: Meningeal neoplasms, Meningioma, WHO grade

How to cite : Gadgil N M, Margam S R, Chaudhari C S, Kumavat P V, The histopathological spectrum of meningeal neoplasms. Indian J Pathol Oncol 2016;3(3):432-436

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