Cytological and histopathological correlation of lymph node swellings

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Original Article

Author Details : Mohammed Abdul Nasar, Mahjabeen Salma, Tazyeen Kouser

Volume : 3, Issue : 3, Year : 2016

Article Page : 427-431

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Abstract

Background & Objectives: Lymph node swellings are one of the commonest clinical presentation of patients and it encompasses a wide spectrum ranging from inflammation to a malignant lymphoma or a more obnoxious metastatic malignancy. The objective of the study was to study the role of FNAC in the evaluating lymph node swellings of various sites in the body and to understand the various cytological patterns of FNAC in correlation with histopathology of lymph node swelling.
Methods: Patients referred to the Department of Pathology, Deccan College of Medical Sciences and Hospital and its allied branches, Princess Esra Hospital for palpable lymph node swelling on whom FNAC procedure was performed were included in the study. FNAC diagnosis of patients was compared with histopathology in cases which underwent surgical excision and its diagnostic accuracy was studied.
Results: Out of 300 cases which included in the study, lymph node biopsy was carried out in 100 cases. Most were in 31 to 40 years. Gender wise, there was female preponderance. Cervical group of lymph node were most affected. Benign lymphadenopathies were diagnosed in 81% of cases. Metastatic deposits were diagnosed in 14% of cases. Lymphomas contributed to 5% cases. On correlation of FNAC findings with histipathology, overall correlation rate was 93%.
Interpretation & Conclusion: FNAC of lymph nodes is an excellent first line method to investigate the nature of lesions as it is economical and an easy alternative to open biopsy.

Keywords: FNAC, Histopathologicay, Biopsy

How to cite : Nasar M A, Salma M, Kouser T, Cytological and histopathological correlation of lymph node swellings. Indian J Pathol Oncol 2016;3(3):427-431

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