Metastatic GIST with a TWIST of RCC: A case report

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Case Report

Author Details : Vaishnavi Ganesan*, Mrunal Kesari, Yoganand Patil, Indranil Bhattacharya

Volume : 11, Issue : 2, Year : 2024

Article Page : 199-201

https://doi.org/10.18231/j.ijpo.2024.043

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Abstract

Aim: Gastrointestinal Stromal Tumors (GIST) is a tumor of mesenchymal origin in the digestive tract, arising from Interstitial cells of Cajal. Majorly, they are an incidental finding in people of older age group (>60 years) with very rare bone metastasis. Our aim is to understand the role of genetic mutations in metastasis of GIST and coexistence of other malignancy in the same patient.
Case Report: We present an unusual case of a 75-year-old male with jejunal GIST, managed with resection of the tumor and imatinib, who 15 years later presented with subsequent liver, rare femoral head metastases and coexisting Renal Cell Carcinoma in left kidney.
Conclusion: GIST cases can be associated with different syndromes and malignancies. This necessitates additional work up and long term follow up.
 

Keywords: GIST, Bone Metastasis, RCC, Tyrosine kinase.

How to cite : Ganesan V, Kesari M, Patil Y, Bhattacharya I, Metastatic GIST with a TWIST of RCC: A case report. Indian J Pathol Oncol 2024;11(2):199-201

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