A primary leiomyosarcoma of small intestine: A rare case report

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Case Report

Author Details : Krishna Kanubhai Patel, Gayatri Ajay Bamaniya*, Cherry K Shah

Volume : 11, Issue : 2, Year : 2024

Article Page : 195-198

https://doi.org/10.18231/j.ijpo.2024.042

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Abstract

Primary leiomyosarcoma of small intestine originating from smooth muscle cell is extremely rare entity. It mimics gastrointestinal stromal tumor (GIST) because of their common morphological appearance. Microscopic and immunochemistry findings are necessary to differentiate Leiomyosarcoma from gastrointestinal tumor (GIST). We report a case of 58-year-old male patient presented to tertiary care hospital with complain of generalized abdominal pain, vomiting, early satiety and constipation. Physical examination revealed no significant findings. Imaging findings showed Ileo-Ileal intussusceptions. Neither CT scan nor MRI reveal any evidence of tumor. The patient underwent exploratory laparotomy which revealed polypoidal mass in ileum. Resection and anastomosis of distal Ileum done & specimen received in histopathology department. On microscopic examination, Diagnosis of GIST & Leiomyosarcoma was considered. Immunohistochemistry was positive for Desmin marker and negative for CD 117, DOG 1, S-100 & ALK marker. The diagnosis of High grade Leiomyosarcoma was confirmed.
 

Keywords: Leiomyosarcoma, Gastrointestinal stromal tumor (GIST), Ileum, Malignant.

How to cite : Patel K K, Bamaniya G A, Shah C K, A primary leiomyosarcoma of small intestine: A rare case report. Indian J Pathol Oncol 2024;11(2):195-198

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