Adenosquamous carcinoma of prostate: An entity out of the ordinary

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Case Report

Author Details : Mansi Agarwal, Saraswathy Sreeram*, Hema Kini

Volume : 10, Issue : 4, Year : 2023

Article Page : 404-405

https://doi.org/10.18231/j.ijpo.2023.091

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Abstract

Adenosquamous carcinoma (ASC) of the prostate is an extremely rare, aggressive histological subtype of prostate cancer. We report one such case here of a 73-year-old man with prostatic malignancy with a combination of squamous and glandular components. Immunohistochemistry with p40, AMACR and HMWCK corroborated the diagnosis of ASC. The squamous component being refractory, is better amenable to aggressive surgery, highlighting the importance of recognising this entity. Bony metastasis was not seen in this patient. Serum PSA was near normal.
 

Keywords: Adenosquamous carcinoma, Gleason score, Immunohistochemistry.

How to cite : Agarwal M, Sreeram S, Kini H, Adenosquamous carcinoma of prostate: An entity out of the ordinary. Indian J Pathol Oncol 2023;10(4):404-405

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