Primary pulmonary NUT midline carcinoma and its diagnostic challenges: A case report

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Case Report

Author Details : Usha Ganugapati, Dominic Ong*

Volume : 9, Issue : 4, Year : 2022

Article Page : 353-356

https://doi.org/10.18231/j.ijpo.2022.085

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Abstract

NUT midline carcinoma (NMC) is a rare and aggressive cancer genetically characterized by a chromosomal rearrangement of the NUT gene. Primary pulmonary NMC is even more rare. NMC typically presents with histological features of a poorly differentiated squamous cell carcinoma. We report a case of a 23-year-old female patient with NMC in the lung and pleura presented to a midsize, midwestern Canadian hospital. This article emphasizes the diagnostic challenges posed by NMC and highlights an encounter with this aggressive cancer, which had not previously been diagnosed in our health region.
 

Keywords: NUT, BRD4, NUT midline carcinoma (NMC)

How to cite : Ganugapati U, Ong D, Primary pulmonary NUT midline carcinoma and its diagnostic challenges: A case report. Indian J Pathol Oncol 2022;9(4):353-356

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