Anti-D alloimmunization after platelet transfusion

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Case Report

Author Details : Ripal J Shah*

Volume : 8, Issue : 2, Year : 2021

Article Page : 306-308

https://doi.org/10.18231/j.ijpo.2021.060

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Abstract

Human platelets do not express any antigens of the Rhesus system. However, platelet concentrates contain the variable volume of contaminating RBCs, which may induce RhD alloimmunization when transfused in a RhD negative subject. Though low rate of anti-D alloimmunization related to platelet transfusion, the development of RhD and non-RhD antibodies cannot be ignored. Thus, transfusion practices could allow the transfusion of RhD positive platelet units to RhD negative patients, with the exception of females of childbearing age.

Keywords: Platelet, Transfusion, Alloimmunization, Donor, Antibody, Antigen.

How to cite : Shah R J , Anti-D alloimmunization after platelet transfusion. Indian J Pathol Oncol 2021;8(2):306-308

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