A histopathological study of renal cell carcinoma at a tertiary care hospital

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Original Article

Author Details : Suresh Mandrekar*, Sangeeta Amoncar, Seeta Pai Raiturkar, Madhumohan Prabhudesai, R G Wiseman Pinto

Volume : 8, Issue : 2, Year : 2021

Article Page : 193-197

https://doi.org/10.18231/j.ijpo.2021.038

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Abstract

Background: Renal cell carcinoma (RCC) accounts for 80-85% of malignant kidney tumors. However incidence of RCC is less in Asian Countries including India and data available from Indian studies is scarce. Outcome of RCC depends on the morphological type and hence accurate classification is essential.
Aims and Objectives: The objective of the present study was to assess the profile of patients of RCC in respect to age distribution, Sex distribution, laterality of the tumor, location within the kidney and Pathological tumor stage and compare our results with available literature from India and other countries.
Material and Methods: The study is a retrospective study, which was conducted over a three and half year period from January 2016 to June 2019 at Goa Medical College, Bambolim Goa. A total of 60 cases of RCC diagnosed over this period were included in the study. Patient details were obtained from the Histopathology requisition forms from the records of Pathology department. The data was collected, analysed and compared with other similar studies. Histopathological examination of the specimens was
conducted using standard processing technique and taking 5 micron sections and staining by Hematoxylin and Eosin technique.
Results: A total of 60 cases of RCC were diagnosed over 3and 12 year period with Clear Cell Carcinoma 38(63.3%) cases being the commonest histopathological type. The tumor was more commonly seen in males with a M:F ratio of 3.6:1. The age ranged from 25 to 78 years with a median of 56.5 years which is decade earlier as compared to Western data. The tumor size(Pathological stage pT) in this study was lower with 24 cases(40%) being diagnosed in pTa stage and 22cases(36.7%) treated with nephron sparing surgery which is a much higher figure as compared to other Indian studies.

Keywords: Renal cell carcinoma, Clear cell, Chromophobe, Multilocular cystic, Papillary.

How to cite : Mandrekar S , Amoncar S , Raiturkar S P , Prabhudesai M , Pinto R G W , A histopathological study of renal cell carcinoma at a tertiary care hospital. Indian J Pathol Oncol 2021;8(2):193-197

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