Granulocytic sarcoma presenting as a palpable breast lump in a 13-year-old female as a relapse of AML

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Case Report

Author Details : Toyaja Jadhav, Ganesh Pendkur, Puneet Baveja*

Volume : 7, Issue : 4, Year : 2020

Article Page : 669-673

https://doi.org/10.18231/j.ijpo.2020.132

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Abstract

Granulocytic sarcoma, also known as myeloid sarcoma or chloroma, is a neoplasm of the myeloid cells that can arise before, concurrent with or following haematolymphoid malignancies, mostly associated with Acute Myeloid Leukaemia (AML). It is an uncommon extramedullary manifestation of AML. We report the case of a 13-year-old girl who presented with a painless lump in her breast. Her past medical history revealed AML, treated and considered in remission. A biopsy was performed in the palpable mass and the histopathological findings were consistent with a Granulocytic sarcoma of the breast, which was considered as a relapse of AML.

Keywords: Acute myeloid leukaemia, Granulocytic sarcoma, Myeloid sarcoma, t(8;21), CD56, CD99

How to cite : Jadhav T , Pendkur G, Baveja P , Granulocytic sarcoma presenting as a palpable breast lump in a 13-year-old female as a relapse of AML. Indian J Pathol Oncol 2020;7(4):669-673

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