Juvenile Myelomonocytic Leukemia (JMML) presenting as bilateral periorbital swelling in a ten year old - A case report

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Case Report

Author Details : Poonam Arora*, Manisha Jain, M L Gupta

Volume : 7, Issue : 4, Year : 2020

Article Page : 657-660

https://doi.org/10.18231/j.ijpo.2020.129

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Abstract

Juvenile Myelomonocytic Leukemia (JMML) is an infrequent pediatric myelodysplastic – myeloproliferative neoplasm characterized by the proliferation of myelomonocytic cells. The incidence of JMML is estimated to be 0.13 cases annually per 100000 children aged from 0-14 years. JMML is difficult to diagnose due to its similar clinical and bone marrow findings with that of other myeloproliferative neoplasms such as Chronic Myeloid Leukemia. Some characteristic features that establish the diagnosis of JMML are the presence of monocytosis (>/=1x 109/L), blast percentage in blood and bone marrow of <20>.

Keywords: Juvenile myelomonocytic leukemia (JMML), Myelodysplastic-myeloproliferative neoplasm, Monocytosis, Periorbital swelling.

How to cite : Arora P , Jain M, Gupta M L , Juvenile Myelomonocytic Leukemia (JMML) presenting as bilateral periorbital swelling in a ten year old - A case report. Indian J Pathol Oncol 2020;7(4):657-660

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