Author Details :
Volume : 7, Issue : 1, Year : 2020
Article Page : 58-62
Introduction: Cancer cervix is a leading cause of mortality and morbidity in developing countries like
India. In developing countries, cervical cancer is the most common cancer cause of death among women.
Developing countries accounted for about 80% of the global burden.
Aim: To study the cervical cytology in 500 cervical Pap smears and classify the smears according to
Bethesda 2014. To highlight the importance of Pap smear study in differentiating premalignant and
Materials and Methods: In this retrospective study, a total of 500 Papaincolaou smears with age group
of 20 to 75 years coming to the cytology section of Pathology department, Mysore Medical College and
Research institute, Mysore, during the time period of 1st April 2018 to 31st August 2018.
Results: In this study, out of 500 cases maximum cases were of negative for intraepithelial lesion or
malignancy 416 cases (83.2%) followed by low-grade squamous intraepithelial lesion with 6 cases (1.2%),
followed by high-grade squamous intraepithelial lesion with 5 cases (1%) then atypical glandular cells of
undetermined significance 3 cases (0.6%) and minimum number of carcinoma cases 02 (0.4% - including
0.4% of squamous cell carcinoma and 0% of adenocarcinoma).
Conclusion: Cervical cytology by Pap smear is an important tool for early detection of premalignant and
malignant lesions of cervix. Regular Pap smear screening should be conducted in vulnerable age group.
Keywords: Bethesda system, Cervical cancer, Pap smear.
How to cite : Aruna Lahari N, Bharathi M, Application of Bethesda system to study cytological pattern of cervical papaincolaou smear in 500 cases at a tertiary care centre. Indian J Pathol Oncol 2020;7(1):58-62
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