Amyloid associated infiltrative cardiomyopathy with Waldenstrom’s Macroglobulinemia

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Case Report

Author Details : Poornakala S, Richa Bhartiya*, Nina Desai, Neha Pokharna

Volume : 6, Issue : 4, Year : 2019

Article Page : 714-716

https://doi.org/10.18231/j.ijpo.2019.135

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Abstract

Amyloidosis is a rare systemic disease characterised by deposition of misfolded aberrant precursor protein,
which forms fibrils in beta-pleated sheets. Waldenstrom’s macroglobulinemiais one of the uncommon
causes of systemic amyloidosis. Diagnosis of systemic amyloidosis in Waldenstrom’s Macroglobulinemia
is crucial, as it is one of the indications of treatment. Biomarkers play major role in early detection
of amyloidosis, which is managed by treatment of underlying plasma cell neoplasm with rapidly acting
agents. Here we are presenting a case of 73-year-old male, a case systemic amyloidosis with underlying
Waldenstrom’s Macroglobulinemia.

Keywords: Amyloidosis, Lymphoplasmacytic lymphoma, Plasma cell neoplasm, Abdominal fat biopsy, Biomarkers.

How to cite : Poornakala S, Bhartiya R, Desai N, Pokharna N , Amyloid associated infiltrative cardiomyopathy with Waldenstrom’s Macroglobulinemia. Indian J Pathol Oncol 2019;6(4):714-716

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