Assessment of glycated haemoglobin, total protein and albumin levels in patients with type 2 diabetes mellitus visiting NAUTH, Nnewi

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Original Article

Author Details : R A Analike*, A C Ihim, S C Iweanya, E C Ogbodo, C E Onah

Volume : 6, Issue : 4, Year : 2019

Article Page : 700-703

https://doi.org/10.18231/j.ijpo.2019.132

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Abstract

This is a case-control study designed to assess the glycated haemoglobin, total protein and albumin levels
in patients with type 2 diabetes mellitus visiting NAUTH, Nnewi. A total of 114 subjects comprising of
57 diabetic subjects and 57 controls aged between 40 and 73 years were recruited for the study. The
patients and controls were aged and sex matched. Subsequently, structured questionnaire were used
to obtain patients’ biodata and thereafter, 5mls of blood sample was collected from each patients and
1ml was dispensed into EDTA for the estimation of glycated haemoglobin, and 4ml was dispensed into
plain containers for the determination of serum albumin and total protein levels using standard laboratory
methods. HbA1c, serum albumin and total protein levels were assayed by using immunoturbidimetric
method, Bromo Cresol green Method and Biuret Method respectively. The result revealed that the mean
level of HbA1c was significantly higher in the diabetic subjects when compared with the non diabetic
subjects (9.621.27 Vs 5.580.62; p=<0> protein did not differ significantly when compared between the diabetic patients and control subjects
(p>0.05). This finding implies that there was a poor glycemic control in the diabetic subjects studied.
Therefore, there is need for better management of diabetic patients through medication and use of diet and
exercise.

Keywords: Glycated hemoglobin, Albumin, Total protein, Diabetes Mellitus (DM), Glycemic control.

How to cite : Analike R A, Ihim A C, Iweanya S C, Ogbodo E C, Onah C E, Assessment of glycated haemoglobin, total protein and albumin levels in patients with type 2 diabetes mellitus visiting NAUTH, Nnewi. Indian J Pathol Oncol 2019;6(4):700-703

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