Histopathological study of cutaneous granulomatous lesions

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Original Article

Author Details : Faiyaz Ahmad, Ankita Mittal*, Deepti Arora, Seema Awasthi, Shyamoli Dutta

Volume : 6, Issue : 4, Year : 2019

Article Page : 526-529

https://doi.org/10.18231/j.ijpo.2019.102

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Abstract

Introduction: Cutaneous granulomatous lesions are very common encountered by pathologist and
dermatologists. Granulomatous dermatoses can be seen in infectious as well as non-infectious conditions
leading to chronic inflammation. Clinical features are overlapping, a confirmatory causative finding is
essential for the management of patient as treatment varies greatly according to cause. Histopathology
remains a gold standard for diagnosis as well as further subtyping of granulomatous inflammatory disorders
of skin.
Materials and Methods: A retrospective study of skin lesion biopsies performed for 2 years and 2 months,
from November 2016 to January 2019. Clinical details were obtained from requisition forms and the cases
of granulomatous lesions were diagnosed and subclassified with the help of H&E and special stains.
Result: The study includes 70 cases. A predominance of male were found with M:F ratio of 1.3:1.
21 to 30 years of age group was the commonest for granulomatous lesions with 34.3% of cases. Infectious
granulomatous dermatoses were far high than non-infectious ones. Leprosy remained the major etiology
followed by tuberculosis of skin.
Conclusion: Leprosy contribute the major cause of granulomatous dermatoses in this study.
Histopathology is gold standard for diagnosis and subclassification of cutaneous granulomatous lesion
with a proper history and clinical details.

Keywords: Granuloma, Leprosy, Skin biopsy.

How to cite : Ahmad F, Mittal A, Arora D, Awasthi S , Dutta S, Histopathological study of cutaneous granulomatous lesions. Indian J Pathol Oncol 2019;6(4):526-529

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