DEDIFFERENTIATED ENDOMETRIAL CARCINOMA – A RARE UTERINE MALIGNANCY AND AN ONGOING DIAGNOSTIC DILEMMA

• Dr Shemeera Saidalavi Vellolipadikkal,*  
• Dr Lillykutty Pothen,  
• Nikita James,  
• Dr Rebecca Mathews,  
• Dr.MEETA THOMAS

Abstract

Tumours of uterine corpus are the most common gynaecological malignancies. The clinicopathological features of most of these tumours are well understood; however, dedifferentiated endometrial carcinoma(DEC) still requires a lot of research to establish adequate management guidelines. Here we report two cases of this tumour with a literature review, emphasising morphologic and immunohistochemical features that may help in the differential diagnosis. It is especially important to recognise this subtype of the malignancy due to its fulminant clinical outcomes and a poorer prognosis than high-grade endometrioid carcinoma.

Keywords

Dedifferentiated endometrial carcinoma, endometrial carcinoma, endometrioid carcinoma ,undifferentiated carcinoma, immunohistochemical .