dengue virus: Investigate serological and hematological indicators for predictions

• Priya Laljibhai Bhojani*

Abstract

Abstract Background: Early and precise identification of dengue is crucial for effective treatment and avoiding serious consequences. The current study aims to investigate serological and hematological indicators for predicting dengue virus infection. Materials and Methods: Between january2022 and january2023, a laboratory-based cross-sectional study was conducted among patients who visited SVP Hospital in Ahmedabad, Gujarat. Blood samples from suspected dengue cases were obtained and examined using the quick diagnostic immunochromatography (ICT) method, with hematological parameters being measured. The Mann-Whitney U test was used to compare continuous variables in dengue-infected and uninfected groups. A binary logistic regression analysis was used to assess the relationship between factors and dengue positive. Results: Compared to dengue-negative individuals, dengue-positive subjects had thrombocytopenia, leucopenia, erythrocytosis, high hemoconcentration, low mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC). However, binary logistic regression indicated that platelet count, total leucocyte count, MCH, MCHC, neutrophil count, and lymphocyte count were all significant predictors of dengue positivity. Conclusion: This study identified the characteristics and demographics of dengue-positive cases, as well as their relationships with hematological markers. Furthermore, the identified predictive markers can assist healthcare practitioners in diagnosing and treating dengue patients more quickly, thus lowering the disease's impact.

Keywords

Dengue,Haematology and serology parameters ,Ahembadabad